MedBrief

• Targeted Oxygen Support vs Standard Care: No Clear Winner Maintaining a targeted SpO2 of 90%-96% safely reduces oxygen use but does not significantly increase oxygen-free days in critically-ill patients, a randomized trial shows.
  Medscape Medical News, April 11, 2025
• Autonomous Imaging Device Matches Manual Dermoscopy A study finds that an autonomous imaging device produces high-quality dermoscopic images with improved efficiency compared with a traditional method.
  Medscape Medical News, April 11, 2025
• Can a Breath Test Ferret Out Lung Cancer? An analysis of exhaled breath, using an electronic nose, demonstrates potential for accurately detecting lung cancer in individuals with suspected disease.
  Medscape Medical News, April 11, 2025
• Methotrexate Can Be Stopped in Certolizumab Combo for RA Patients with RA who achieve LDA with certolizumab plus methotrexate had similar rates of worsening symptoms following either stopping or continuing methotrexate.
  Medscape Medical News, April 11, 2025
• No Increased Birth Defect Risk From Smoking Cessation Meds No increase in risk for major congenital malformations is observed in infants born to mothers receiving smoking cessation therapies, according to a large cohort study.
  Medscape Medical News, April 11, 2025
• Popular Joint Supplement Cuts Nephropathy Risk in T2D People with type 2 diabetes who regularly use the supplement glucosamine have a lower risk for microvascular complications and diabetic nephropathy, a prospective observational study finds.
  Medscape Medical News, April 11, 2025
• Novel Blood Thinner Shows Promise in Atrial Fibrillation A recent study reveals that asundexian may reduce the risk for stroke and bleeding in patients with atrial fibrillation and limited prior anticoagulant exposure.
  Medscape Medical News, April 10, 2025
• Lacerations Most Common Ear Injuries in US Over 20 Years A study analyzes two decades of data on traumatic ear injuries, highlighting key demographics and injury patterns across age groups.
  Medscape Medical News, April 10, 2025
• DLBCL: Novel Drug Combo Boosts Survival in Older Adults Innovative polatuzumab vedotin plus R-CHP therapy reshapes treatment of older adult patients with diffuse large B-cell lymphoma.
  Medscape Medical News, April 10, 2025
• Tumor Bacteria Tied to Metachronous CRC in Lynch Syndrome The genotoxic gut bacterium pks+ E coli is enriched in CRCs in people with Lynch syndrome, and its presence within the initial primary tumor is tied to an increased risk for metachronous CRC.
  Medscape Medical News, April 10, 2025
• Genomic Test Findings for Black Women With Breast Cancer A review evaluated the distribution and predictive capabilities of three genomic assays for breast cancer across different racial and ethnic populations.
  Medscape Medical News, April 10, 2025
• Mediterranean Diet and Exercise Boost Bone Health in Seniors An energy-restricted Mediterranean diet plus physical activity can mitigate weight loss and age-related decline in bone mineral density in older women with metabolic syndrome and overweight or obesity.
  Medscape Medical News, April 10, 2025
• Lung Cancer Screening Lower Than Others A study aims to explore whether individuals eligible for lung cancer screening also access other preventive services.
  Medscape Medical News, April 10, 2025
• Knee OA Pain? Yoga, Strengthening Exercises May Help Equally Over a 12-week period, yoga proves noninferior to strengthening exercises in significantly reducing knee pain.
  Medscape Medical News, April 10, 2025
• Cardiac Dysfunction Surfaces Early With Cancer Treatment Cardiac problems associated with vascular endothelial growth factor inhibitors occur frequently in patients with cancer.
  Medscape Medical News, April 10, 2025
• New Scoring System May Streamline Food Allergy Diagnosis The NAPFA score may predict which children have a food allergy, even without allergy test results.
  Medscape Medical News, April 09, 2025
• US Pregnancy-Related Deaths Rise 28% Over 5 Years The United States reports the highest pregnancy-related death rate among high-income countries during 2018-2022.
  Medscape Medical News, April 09, 2025
• Survival After Sudden Cardiac Arrest Rises in Young Athletes Among young competitive athletes in the United States, survival after sudden cardiac arrest has improved over time, but racial disparities persist and warrant emergency preparedness.
  Medscape Medical News, April 09, 2025
• Glucocorticoid Dose Guides PJP Prophylaxis Discontinuation Stopping prophylactic treatment in patients with rheumatic disease on > 12.5 mg/d of prednisone-equivalent corticosteroids raises the risk for Pneumocystis jirovecii pneumonia.
  Medscape Medical News, April 09, 2025
• Modest Effects of Valacyclovir in Herpes Zoster Eye Disease Administration of low-dose valacyclovir over a year does not significantly reduce the occurrence of herpes zoster ophthalmicus but shows potential benefits over time.
  Medscape Medical News, April 09, 2025